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ASMTY Polyclonal Antibody, Cy7 Conjugated

Product Specifications

Background

This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. Isoform 1 catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine) . Isoform 2 and isoform 3 lack enzyme activity

Synonyms

Acetylserotonin O-methyltransferase; ASMT; ASMTY; HIOMT; HIOMTY; Hydroxyindole O-methyltransferase.

Gene ID

438

Swiss Prot

P46597

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Rat

Immunogen

241-345/345

Target

ASMTY

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy7

Source

KLH conjugated synthetic peptide derived from human Acetylserotonin O-methyltransferase (ASMT)

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

743nm/767nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

438

Predicted Cross Reactivity

Human, Mouse, Dog, Cow, Sheep, Horse

Curated Selection

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