Factor B Polyclonal Antibody, PE-Cy5 Conjugated
Product Specifications
Background
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Synonyms
BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14; Complement factor B; C3/C5 convertase; Glycine-rich beta glycoprotein; Properdin factor B; CFB
Gene ID
629
Swiss Prot
P00751
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
301-400/764
Target
Factor B
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE-Cy5
Source
KLH conjugated synthetic peptide derived from human Complement factor-B Bb fragment
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/670nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
629
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
33334-05151 5x 30 µg
Human Alpha-2-macroglobulin Receptor-associated Protein AssayLite™ Antibody (RPE Conjugate)
Sign In for Pricing
View Details 
abx347297 100 Tests
Tyrosine-Protein Phosphatase Non-Receptor Type Substrate 1 (SIRPA) Antibody (PerCP / Cyanine 5.5)
Sign In for Pricing
View Details 