KDEL Polyclonal Antibody, AbBy Fluor™ 680 Conjugated
Product Specifications
Background
Endoplasmic reticulum Marker. The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. 78 and 94 kDa glucose regulated proteins (GRP 78) and GRP 94 respectively and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
Synonyms
KDEL; Lys Asp Glu Leu antibody; GRP 78; GRP 94; KDEL1_HUMAN.
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Mouse, Rat
Target
KDEL
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 680
Source
KLH conjugated synthetic peptide KDEL
Applications
FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
679nm/702nm
Concentration
1µg/µl
Dilution
FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Predicted Cross Reactivity
Human, Dog, Cow, Pig, Rabbit, GuineaPig
More Discoveries
Explore Other Products
Browse additional items from our catalog
K6696203 1.0 µg DNA
Spdef sgRNA CRISPR Lentivector (Rat) (Target 2)
Sign In for Pricing
View Details 132298-HRP 100 µL
RANBP3 (RAN Binding Protein 3, DKFZp586I1520) (HRP)
Sign In for Pricing
View Details MBS1193085-01 0.02 mg (E-Coli)
Recombinant Plasmodium falciparum Reticulocyte binding protein 2 homolog b (Rh2b), partial
Sign In for Pricing
View Details