RING finger protein 189 Antibody, PE Conjugated
Product Specifications
Background
Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates.
Synonyms
CARP-2; CARP2; Caspase regulator CARP2; Caspases 8 and 10 associated RING finger protein 2; Caspases-8 and -10-associated RING finger protein 2; E3 ubiquitin protein ligase rylin; E3 ubiquitin-protein ligase rylin; Fring; FYVE RING finger protein Sakura; FYVE-RING finger protein Sakura; Rffl; RFFL_HUMAN; Rylin; RING finger and FYVE like domain containing protein; RING finger and FYVE-like domain-containing protein 1; RING finger protein 189; RING finger protein 34 like; RING finger protein 34-like; RNF189; RNF34L.
Gene ID
117584
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
251-363/363
Target
RING finger protein 189
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human RING finger protein 189
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
117584
Predicted Cross Reactivity
Rat, Dog, Cow, Sheep, Pig, Rabbit
Curated Selection
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