HBXIP Polyclonal Antibody, PE Conjugated
Product Specifications
Background
HBXIP (Hepatitis B virus X interacting protein) complexes with the C-terminus of hepatitis B virus X protein (HBx) and down-regulates hepatitis B virus (HBV) replication. When complexed to BIRC5, it interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway.
Synonyms
HBV X interacting protein; HBX interacting protein; Hepatitis B virus X interacting protein; MGC71071; XIP; HBXIP_HUMAN.
Gene ID
10542
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Immunogen
41-91/91
Target
HBXIP
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human HBXIP
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
10542
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Pig, Rabbit
Curated Selection
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