HBXIP Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

HBXIP (Hepatitis B virus X interacting protein) complexes with the C-terminus of hepatitis B virus X protein (HBx) and down-regulates hepatitis B virus (HBV) replication. When complexed to BIRC5, it interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway.

Synonyms

HBV X interacting protein; HBX interacting protein; Hepatitis B virus X interacting protein; MGC71071; XIP; HBXIP_HUMAN.

Gene ID

10542

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Immunogen

41-91/91

Target

HBXIP

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human HBXIP

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

10542

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Pig, Rabbit

Curated Selection

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