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Beta COP Polyclonal Antibody, HRP Conjugated

Product Specifications

Background

The Golgi complex is a key organelle where processing and sorting of newly synthesized proteins occurs. Membrane traffic from the endoplasmic reticulum (ER) to the Golgi complex and from the Golgi complex to the different final cellular destinations is believed to be mediated by carrier vesicles. Two populations of coated vesicles mediate biosynthetic membrane traffic between the different membrane-bound compartments. Clathrin-coated vesicles carry proteins to endocytic organelles and secretory granules, whilst non-clathrin-coated vesicles are involved in intra-Golgi transport and transport from the ER to the Golgi complex. Beta COP is a member of a set of protein which are believed to associate with the non-clathrin coated vesicles. Golgi-derived non-clathrin-coated vesicles are believed to act as bulk carriers, whereas clathrin-coated vesicles carry a selective cargo of membrane proteins.

Synonyms

Beta-coat protein; betacop; Coatomer beta subunit; Coatomer protein complex subunit beta 1; Coatomer protein complex subunit beta; Coatomer subunit beta; COPB; COPB1; DKFZp761K102; FLJ10341.

Gene ID

1315

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Immunogen

531-630/953

Target

Beta COP

Clonality

Polyclonal

Isotype

IgG

Conjugation

HRP

Source

KLH conjugated synthetic peptide derived from human beta COP

Applications

ELISA, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1315

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Pig, Horse, Chicken

Curated Selection

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