Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Phospho-MAP3K9+MAP3K10 (Thr312 + Thr266) Polyclonal Antibody, APC-Cy5.5 Conjugated

Product Specifications

Background

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.

Synonyms

MLK1; MEKK9; PRKE1; Mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; MAP3K9

Gene ID

4293

Swiss Prot

P80192

Modification Site

Thr312

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

Phospho-MAP3K9+MAP3K10 (Thr312 + Thr266)

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy5.5

Source

KLH conjugated synthetic phosphopeptide derived from human MAP3K9 around the phosphorylation site of Thr312

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/694nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4293

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit

More Discoveries

Explore Other Products

Browse additional items from our catalog

NOS2 Rabbit Polyclonal Antibody
E53P08341 100 µL

NOS2 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Human TSHR/LGR3 Antibody , PE
E55A10332 50 Tests

Human TSHR/LGR3 Antibody , PE

Sign In for Pricing
View Details
Rat Annexin A2 (ANXA2) ELISA Kit
MBS457650-01 48 Tests

Rat Annexin A2 (ANXA2) ELISA Kit

Sign In for Pricing
View Details
Rat Annexin A2 (ANXA2) ELISA Kit
MBS457650-02 96 Tests

Rat Annexin A2 (ANXA2) ELISA Kit

Sign In for Pricing
View Details
Rat Annexin A2 (ANXA2) ELISA Kit
MBS457650-03 5x 96 Tests

Rat Annexin A2 (ANXA2) ELISA Kit

Sign In for Pricing
View Details
Rat Annexin A2 (ANXA2) ELISA Kit
MBS457650-04 10x 96 Tests

Rat Annexin A2 (ANXA2) ELISA Kit

Sign In for Pricing
View Details