TMEM49 Polyclonal Antibody
Product Specifications
Background
Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1 (By similarity) . Involved in cell-cell adhesion. Plays an essential role in formation of cell junctions.
Synonyms
EPG3; TANGO5; TMEM49; Vacuole membrane protein 1; Transmembrane protein 49; VMP1; TDC1; HSPC292
Gene ID
81671
Swiss Prot
Q96GC9
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
361-406/406
Target
TMEM49
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human TMEM49
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
81671
Predicted Cross Reactivity
Human, Rat, Pig, Horse, Rabbit
Curated Selection
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