UGDH Polyclonal Antibody, Cy7 Conjugated

Product Specifications

Background

The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010].

Synonyms

UDP glucose dehydrogenase; GDH; UDP Glc dehydrogenasev UDP GlcDH; UDP glucose 6 dehydrogenase; UDP-Glc dehydrogenase; UDP-GlcDH; UDP-glucose 6-dehydrogenase; UDPGDH; UGD; Ugdh; UGDH_HUMAN; Uridine diphospho glucose dehydrogenase.

Gene ID

7358

Cellular Locus

Cytoplasm, Nucleus, Secreted, Extracellular matrix

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

421-494/494

Target

UGDH

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy7

Source

KLH conjugated synthetic peptide derived from human UGDH/UDPGDH

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

743nm/767nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

7358

Predicted Cross Reactivity

Dog, Cow, Sheep, Pig, Horse, Rabbit

Curated Selection

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