GIRK1/KCNJ3 Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.
Synonyms
KGA; GIRK1; KIR3.1; G protein-activated inward rectifier potassium channel 1; GIRK-1; Inward rectifier K (+) channel Kir3.1; Potassium channel, inwardly rectifying subfamily J member 3; KCNJ3
Gene ID
3760
Swiss Prot
P48549
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
81-180/501
Target
GIRK1/KCNJ3
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic peptide derived from human GIRK1
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3760
Predicted Cross Reactivity
Human, Dog, Cow, Pig, Rabbit, GuineaPig
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