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GIRK1/KCNJ3 Polyclonal Antibody, APC Conjugated

Product Specifications

Background

This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

Synonyms

KGA; GIRK1; KIR3.1; G protein-activated inward rectifier potassium channel 1; GIRK-1; Inward rectifier K (+) channel Kir3.1; Potassium channel, inwardly rectifying subfamily J member 3; KCNJ3

Gene ID

3760

Swiss Prot

P48549

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

81-180/501

Target

GIRK1/KCNJ3

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human GIRK1

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3760

Predicted Cross Reactivity

Human, Dog, Cow, Pig, Rabbit, GuineaPig

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