Mesopram
Mesopram (Daxalipram) is an orally active phosphodiesterase (PDE) 4 inhibitor. Mesopram inhibits the synthesis of proinflammatory cytokines TNF-α and IFN-γ. Mesopram demonstrates efficacy in ameliorating Dextran sulfate sodium (DSS) -induced murine colitis. Mesopram can be used for the study of chronic inflammatory diseases[1][2].
Product Specifications
CAS Number
189940-24-7
Product Name Alternative
Daxalipram
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
IFNAR; Interleukin Related; Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mesopram.html
Purity
98.80
Solubility
10 mM in DMSO
Smiles
O=C1O[C@](C)(C2=CC=C(OC)C(OCCC)=C2)CN1
Molecular Formula
C14H19NO4
Molecular Weight
265.30
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
PDE4
Available Sizes
Frequently Asked Questions
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