HSPA6 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Sequence similarities Belongs to the heat shock protein 70 family.

Synonyms

Heat shock 70 kDa protein 6; Heat shock 70 kDa protein B; heat shock 70kD protein 6 HSP70B'; Heat shock 70kDa protein 6; HSP70B; HSP76_HUMAN; HSPA6.

Gene ID

3310

Cellular Locus

Cytoplasm, Secreted, Extracellular matrix

Host

Rabbit

Immunogen

451-550/643

Target

HSPA6

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human HSPA6

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3310

Predicted Cross Reactivity

Human, Mouse, Rat, Cow, Sheep

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