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ABH8 Polyclonal Antibody, APC Conjugated

Product Specifications

Background

Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA (Arg) and tRNA (Glu), and does not bind tRNA (Lys) . Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.

Synonyms

ABH8; alkB alkylation repair homolog 8 E. coli; alkB alkylation repair homolog 8; AlkB homologue 8; ALKB8_HUMAN; ALKBH8; Alkylated DNA repair protein alkB homolog 8; Probable alpha-ketoglutarate-dependent dioxygenase ABH8; S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8.

Gene ID

91801

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Rat

Immunogen

245-350/664

Target

ABH8

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human ABH8/ALKBH8

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

91801

Predicted Cross Reactivity

Human, Mouse, Dog, Horse, Chicken, Rabbit

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