Unc18-3 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.

Synonyms

Munc 18 3; Munc18 3; Munc 18-3; Protein unc-18 homolog 3; STXB3_HUMAN.

Gene ID

6814

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Immunogen

165-260/592

Target

Unc18-3

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human Unc18-3

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6814

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Pig, Rabbit

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