Unc18-3 Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
Synonyms
Munc 18 3; Munc18 3; Munc 18-3; Protein unc-18 homolog 3; STXB3_HUMAN.
Gene ID
6814
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Immunogen
165-260/592
Target
Unc18-3
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic peptide derived from human Unc18-3
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
6814
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Pig, Rabbit
Curated Selection
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