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NFATC4 Polyclonal Antibody, Cy5 Conjugated

Product Specifications

Background

Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL-4. Transcriptionally repressed by estrogen receptors; this inhibition is further enhanced by estrogen. Increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. May play an important role in myotube differentiation. May play a critical role in cardiac development and hypertrophy. May play a role in deafferentation-induced apoptosis of sensory neurons.

Synonyms

NFAT3; NF-AT3; NF-ATC4; Nuclear factor of activated T-cells, cytoplasmic 4; NFATc4; T-cell transcription factor NFAT3

Gene ID

4776

Swiss Prot

Q14934

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

475-525/902

Target

NFATC4

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy5

Source

KLH conjugated synthetic peptide derived from human NF-ATc4

Applications

WB, IF (IHC-P)

Purification

Purified by Protein A.

Excitation Emission

625,650nm/670nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4776

Predicted Cross Reactivity

Human, Dog, Cow, Sheep, Pig, Horse

Curated Selection

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