ABCA2 Polyclonal Antibody, PE Conjugated
Product Specifications
Background
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene (from EntrezGene) .
Synonyms
ABC2; ATP binding cassette 2; ATP binding cassette sub family A member 2; ATP binding cassette transporter 2; ATP binding cassette, sub family A ABC1, member 2; ATP binding cassette, sub family A, member 2; ATP binding cassette, sub family B MDR/TAP, member 2; ABCA2_HUMAN.
Gene ID
20
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Immunogen
1901-2100/2435
Target
ABCA2
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human ABCA2
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
20
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Horse
Curated Selection
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