GLUT10 Polyclonal Antibody, FITC Conjugated
Product Specifications
Background
Defects in SLC2A10 are the cause of arterial tortuosity syndrome (ATS) [MIM:208050]. ATS is an autosomal recessive disorder characterized by tortuosity and elongation of major arteries, often resulting in death at young age. Other typical features include aneurysms of large arteries and stenosis of the pulmonary artery, in association with facial features and several connective tissue manifestations such as soft skin and joint laxity. Histopathological findings include fragmentation of elastic fibers in the tunica media of large arteries.
Synonyms
ATS; GLUT10; Solute carrier family 2, facilitated glucose transporter member 10; Glucose transporter type 10; GLUT-10; SLC2A10
Gene ID
81031
Swiss Prot
O95528
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Immunogen
288-335/541
Target
GLUT10
Clonality
Polyclonal
Isotype
IgG
Conjugation
FITC
Source
KLH conjugated synthetic peptide derived from human GLUT10
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
494nm/518nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
81031
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow
Curated Selection
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