GLUT10 Polyclonal Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

Defects in SLC2A10 are the cause of arterial tortuosity syndrome (ATS) [MIM:208050]. ATS is an autosomal recessive disorder characterized by tortuosity and elongation of major arteries, often resulting in death at young age. Other typical features include aneurysms of large arteries and stenosis of the pulmonary artery, in association with facial features and several connective tissue manifestations such as soft skin and joint laxity. Histopathological findings include fragmentation of elastic fibers in the tunica media of large arteries.

Synonyms

ATS; GLUT10; Solute carrier family 2, facilitated glucose transporter member 10; Glucose transporter type 10; GLUT-10; SLC2A10

Gene ID

81031

Swiss Prot

O95528

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Immunogen

288-335/541

Target

GLUT10

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic peptide derived from human GLUT10

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

81031

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow

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