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WISP1 Polyclonal Antibody, HRP Conjugated

Product Specifications

Background

Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X (L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.

Synonyms

CCN4; WISP1c; WISP1i; WISP1tc; WNT1-inducible-signaling pathway protein 1; WISP-1; CCN family member 4; Wnt-1-induced secreted protein; WISP1

Gene ID

8840

Swiss Prot

O95388

Cellular Locus

Secreted

Host

Rabbit

Immunogen

237-295/367

Target

WISP1

Clonality

Polyclonal

Isotype

IgG

Conjugation

HRP

Source

KLH conjugated synthetic peptide derived from human WISP1

Applications

ELISA, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8840

Predicted Cross Reactivity

Human, Mouse, Rat, Rabbit

Available Sizes

Curated Selection

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