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Dyrk1B Polyclonal Antibody, PE-Cy5.5 Conjugated

Product Specifications

Background

Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC) .

Synonyms

MIRK; AOMS3; Dual specificity tyrosine-phosphorylation-regulated kinase 1B; Minibrain-related kinase; Mirk protein kinase; DYRK1B

Gene ID

9149

Swiss Prot

Q9Y463

Cellular Locus

Nucleus

Host

Rabbit

Immunogen

35-130/629

Target

Dyrk1B

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy5.5

Source

KLH conjugated synthetic peptide derived from human MIRK/Dyrk1B

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/694nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

9149

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Pig

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