Phospho-BCAR1 (Tyr410) Polyclonal Antibody, APC Conjugated
Product Specifications
Background
Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.
Synonyms
CAS; CAS1; CASS1; CRKAS; P130Cas; Breast cancer anti-estrogen resistance protein 1; CRK-associated substrate; Cas scaffolding protein family member 1; BCAR1
Gene ID
9564
Swiss Prot
P56945
Modification Site
Tyr410
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Rat
Target
Phospho-BCAR1 (Tyr410)
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic phosphopeptide derived from human BCAR1 around the phosphorylation site of Tyr410.
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
Will recognize BCAR1 (Tyr414) in mouse and BCAR1 (Tyr508) in rat
Gene ID URL
9564
Predicted Cross Reactivity
Human, Mouse, Horse
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
