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Alpha 2 antiplasmin Polyclonal Antibody, PE Conjugated

Product Specifications

Background

Alpha 2 Antiplasmin is a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

A2AP; A2AP_HUMAN; AAP; Alpha 2 antiplasmin; Alpha 2 antiplasmin pigment epithelium derived factor; Alpha 2 AP; ALPHA 2 PI; Alpha 2 plasmin inhibitor; Alpha 2 plasmin inhibitor deficiency; Alpha-2-antiplasmin; Alpha-2-AP; Alpha-2-PI; Alpha-2-plasmin inhibitor; Antiplasmin deficiency; API; Plasmin inhibitor deficiency; PLI; Serine or cysteine peptidase inhibitor, clade F, member 2; Serine Or cysteine peptidase inhibitor, clade F, member 2, isoform CRA_c; Serine or cysteine proteinase inhibitor, clade F alpha 2 antiplasmin pigment epithelium derived factor member 2; Serine Or cysteine proteinase inhibitor, clade F, member 2; Serine or cysteine peptidase inhibitor clade F member 2; Serpin F2; Serpin peptidase inhibitor clade F; Serpin peptidase inhibitor, clade F alpha 2 antiplasmin pigment epithelium derived factor member 2; SERPINF2.

Gene ID

5345

Swiss Prot

P08697

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

161-260/491

Target

Alpha 2 antiplasmin

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE

Source

KLH conjugated synthetic peptide derived from human SERPINF2/Alpha 2 antiplasmin

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5345

Predicted Cross Reactivity

Dog, Horse, Rabbit

Curated Selection

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