Alpha 2 antiplasmin Polyclonal Antibody
Product Specifications
Background
Alpha 2 Antiplasmin is a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
A2AP; A2AP_HUMAN; AAP; Alpha 2 antiplasmin; Alpha 2 antiplasmin pigment epithelium derived factor; Alpha 2 AP; ALPHA 2 PI; Alpha 2 plasmin inhibitor; Alpha 2 plasmin inhibitor deficiency; Alpha-2-antiplasmin; Alpha-2-AP; Alpha-2-PI; Alpha-2-plasmin inhibitor; Antiplasmin deficiency; API; Plasmin inhibitor deficiency; PLI; Serine or cysteine peptidase inhibitor, clade F, member 2; Serine Or cysteine peptidase inhibitor, clade F, member 2, isoform CRA_c; Serine or cysteine proteinase inhibitor, clade F alpha 2 antiplasmin pigment epithelium derived factor member 2; Serine Or cysteine proteinase inhibitor, clade F, member 2; Serine or cysteine peptidase inhibitor clade F member 2; Serpin F2; Serpin peptidase inhibitor clade F; Serpin peptidase inhibitor, clade F alpha 2 antiplasmin pigment epithelium derived factor member 2; SERPINF2.
Gene ID
5345
Swiss Prot
P08697
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
161-260/491
Target
Alpha 2 antiplasmin
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human SERPINF2/Alpha 2 antiplasmin
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
5345
Predicted Cross Reactivity
Dog, Horse, Rabbit
Curated Selection
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