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C1 Inactivator Polyclonal Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

C1 Inactivator is a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE) . Alternative splicing results in multiple transcript variants encoding the same isoform.

Synonyms

C1 esterase inhibitor; C1 INH; C1 inhibitor; C1-inhibiting factor; C1IN; C1Inh; C1NH; esterase inhibitor; HAE1; IC1_HUMAN; Plasma protease C1 inhibitor; Serine or cysteine proteinase inhibitor clade G member 1; Serpin G1; SERPING1.

Gene ID

710

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Human

Immunogen

401-500/500

Target

C1 Inactivator

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic peptide derived from human SERPING1

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

710

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Pig, GuineaPig

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