Rab3A+Rab3B+Rab3C+Rab3D Antibody, FITC Conjugated
Product Specifications
Background
Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has four known isoforms: 3A, 3B, 3C and 3D. These proteins are expressed in the highest concentration in the brain and endocrine tissues and are involved in regulated exocytosis of hormones and neurotransmitters. Specifically Rab3's are thought to play a role in presynaptic vesicle trafficking and priming.
Synonyms
RAB3A; RAB3A member RAS oncogene family; RAB3B; RAB3B member RAS oncogene family; RAB3C; RAB3C member RAS oncogene family; RAB3D member RAS oncogene family; RAD3D; Ras related protein Rab 3A; Ras related protein Rab 3B; Ras related protein Rab 3C; Ras related protein Rab 3D; D2 2; Glioblastoma overexpressed; GOV; RAB16.
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
101-150/220
Target
Rab3A+Rab3B+Rab3C+Rab3D
Clonality
Polyclonal
Isotype
IgG
Conjugation
FITC
Source
KLH conjugated synthetic peptide derived from human Rab3A+Rab3B+Rab3C+Rab3D
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
494nm/518nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Predicted Cross Reactivity
Human
Curated Selection
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