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POU6F2 Polyclonal Antibody, PE-Cy5.5 Conjugated

Product Specifications

Background

This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Synonyms

POU class 6 homeobox 2; POU domain class 6 transcription factor 2; Retina derived POU domain factor 1; RPF 1; RPF1; Wilms tumor suppressor locus; WT 5; WT5; WTSL; PO6F2_HUMAN.

Gene ID

11281

Cellular Locus

Nucleus

Host

Rabbit

Immunogen

531-640/691

Target

POU6F2

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy5.5

Source

KLH conjugated synthetic peptide derived from human POU6F2

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/694nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

11281

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Sheep, Pig, Horse, Chicken, Rabbit

Curated Selection

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