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MCC Polyclonal Antibody, APC Conjugated

Product Specifications

Background

This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Synonyms

Colorectal mutant cancer protein; MCC 1; MCC-1; MCC1; Mutated in colorectal cancers; Protein MCC; CRCM_HUMAN.

Gene ID

4163

Swiss Prot

P23508

Cellular Locus

Nucleus, Cell membrane

Host

Rabbit

Immunogen

731-829/829

Target

MCC

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human MCC

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4163

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Pig, Horse

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