Phospho-LLGL1 + LLGL2 (Ser650+Ser654) Polyclonal Antibody, AbBy Fluor™ 405 Conjugated
Product Specifications
Background
LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC) . In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
Synonyms
LLGL1 + LLGL2 phospho S650 + S654; LLGL1 + LLGL2 phospho Ser650 + Ser654; p-LLGL1 + p-LLGL2 S650 + S654; p-LLGL1/LLGL2 Ser650 + Ser654; p-LLGL1/LLGL2 S650 + S654; p-LLGL1/LLGL2 Ser650/654; DLG4; HGL; HUGL; HUGL1; lethal giant larvae homolog 1; lethal giant larvae homolog 2; Lethal2 giant larvae protein homolog 1; Lethal2 giant larvae protein homolog 2; LGL2; LLGL; L2GL1_HUMAN; L2GL2_HUMAN.
Gene ID
3996
Modification Site
Ser650+Ser654
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Rat
Target
Phospho-LLGL1 + LLGL2 (Ser650+Ser654)
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 405
Source
KLH conjugated synthetic phosphopeptide derived from mouse LLGL1 around the phosphorylation site of Ser650+Ser654
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
401nm/421nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3996
Predicted Cross Reactivity
Human, Mouse, Dog, Cow, Pig, Horse, Chicken, Guinea Pig
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
FUF156-2pcs 2 PCS/Pack
Ultrafiltration Spin Columns (15ml, 50kDa MWCO, PES, Sartorius)
Ask
View Details ![Mouse Monoclonal Pentraxin 2/SAP Antibody (APCS/3240) [Alexa Fluor 700]](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
NBP2-79848AF700 0.1 mL
Mouse Monoclonal Pentraxin 2/SAP Antibody (APCS/3240) [Alexa Fluor 700]
Ask
View Details 
