Nicastrin Polyclonal Antibody, Cy5 Conjugated

Product Specifications

Background

Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein) . It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.

Synonyms

ATAG1874; Nicastrin; NCSTN; KIAA0253; UNQ1874/PRO4317

Gene ID

23385

Swiss Prot

Q92542

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

21-120/709

Target

Nicastrin

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy5

Source

KLH conjugated synthetic peptide derived from human Nicastrin

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

625,650nm/670nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

23385

Predicted Cross Reactivity

Mouse, Rat, Cow, Pig, Horse, Chicken

Curated Selection

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