Nicastrin Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein) . It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.

Synonyms

ATAG1874; Nicastrin; NCSTN; KIAA0253; UNQ1874/PRO4317

Gene ID

23385

Swiss Prot

Q92542

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

21-120/709

Target

Nicastrin

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human Nicastrin

Applications

WB, ELISA, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

23385

Predicted Cross Reactivity

Mouse, Rat, Cow, Pig, Horse, Chicken

Curated Selection

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