DLL4 Polyclonal Antibody, PE Conjugated
Product Specifications
Background
Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.
Synonyms
Hdelta2; Delta-like protein 4; Drosophila Delta homolog 4; Delta4; DLL4; UNQ1895/PRO4341
Gene ID
54567
Swiss Prot
Q9NR61
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Rat
Immunogen
551-650/685
Target
DLL4
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human DLL4
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
54567
Predicted Cross Reactivity
Mouse, Dog, Cow, Pig, Horse
Curated Selection
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