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DLL4 Polyclonal Antibody, APC Conjugated

Product Specifications

Background

Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.

Synonyms

Hdelta2; Delta-like protein 4; Drosophila Delta homolog 4; Delta4; DLL4; UNQ1895/PRO4341

Gene ID

54567

Swiss Prot

Q9NR61

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

551-650/685

Target

DLL4

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human DLL4

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

54567

Predicted Cross Reactivity

Mouse, Dog, Cow, Pig, Horse

Curated Selection

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