Phospho-CD32 (Tyr292) Polyclonal Antibody, AbBy Fluor™ 680 Conjugated
Product Specifications
Background
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Synonyms
CD32; FCG2; CD32B; FCGR2; IGFR2; Low affinity immunoglobulin gamma Fc region receptor II-b; IgG Fc receptor II-b; CDw32; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; FCGR2B
Gene ID
2213
Swiss Prot
P31994
Modification Site
Tyr292
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Monkey
Target
Phospho-CD32 (Tyr292)
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 680
Source
KLH conjugated synthetic phosphopeptide derived from human CD32B around the phosphorylation site of Tyr292.
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
679nm/702nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
2213
Predicted Cross Reactivity
Rat, Dog, Sheep, Pig, Rabbit, Guinea Pig
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
133921-APC 100 µL
STAMBP (STAM-binding Protein, Associated Molecule with the SH3 Domain of STAM, AMSH, Endosome-associated Ubiquitin Isopeptidase) (APC)
Ask
View Details 
