RBBP5 Polyclonal Antibody, APC Conjugated

Product Specifications

Background

In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid (By similarity) . As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.

Synonyms

RBQ3; SWD1; Retinoblastoma-binding protein 5; RBBP-5; Retinoblastoma-binding protein RBQ-3; RBBP5

Gene ID

5929

Swiss Prot

Q15291

Cellular Locus

Nucleus

Host

Rabbit

Immunogen

131-230/538

Target

RBBP5

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human RBBP5

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5929

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Horse, Chicken, Rabbit

Curated Selection

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