MAS1 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Receptor for angiotensin 1-7 (By similarity) . Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.

Synonyms

MAS; MGRA; Proto-oncogene Mas; MAS1

Gene ID

4142

Swiss Prot

P04201

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

51-150/325

Target

MAS1

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human MAS1

Applications

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4142

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit, GuineaPig

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