Calreticulin Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity) .
Synonyms
RO; CRT; SSA; cC1qR; HEL-S-99n; Calreticulin; CRP55; Calregulin; Endoplasmic reticulum resident protein 6; ERp6; HACBP; grp6; CALR; CRTC
Gene ID
811
Swiss Prot
P27797
Cellular Locus
Cytoplasm, Secreted, Cell membrane, Extracellular matrix
Host
Rabbit
Cross Reactivity
Human
Immunogen
101-200/417
Target
Calreticulin
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human Calreticulin
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
811
Curated Selection
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