Calreticulin Polyclonal Antibody

Product Specifications

Background

Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (By similarity) .

Synonyms

RO; CRT; SSA; cC1qR; HEL-S-99n; Calreticulin; CRP55; Calregulin; Endoplasmic reticulum resident protein 6; ERp6; HACBP; grp6; CALR; CRTC

Gene ID

811

Swiss Prot

P27797

Cellular Locus

Cytoplasm, Secreted, Cell membrane, Extracellular matrix

Host

Rabbit

Cross Reactivity

Human

Immunogen

101-200/417

Target

Calreticulin

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human Calreticulin

Applications

WB, ELISA, FCM, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)