DBF4B Polyclonal Antibody
Product Specifications
Background
DBF4B is a regulatory subunit for CDC7, a serine-threonine kinase which links cell cycle regulation to genome duplication. The complex CDC7-DBF4B selectively phosphorylates the MCM2 subunit at 'Ser-40' and then is involved in regulating the initiation of DNA replication during cell cycle. DBF4B localizes to the nucleus and its expression is cell cycle-regulated.
Synonyms
Activator of S phase kinase like protein 1; ASK like protein 1; ASKL1; chb; Chfon homolog B; DBF 4B; DBF4 homolog B S. cerevisiae; DBF4 homolog B; Dbf4 related factor 1; DRF1; Protein DBF4 homolog B; ZDBF1B; Zinc finger DBF type containing 1B; DBF4B_HUMAN.
Gene ID
80174
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Immunogen
41-140/615
Target
DBF4B
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human DBF4B/ASKL1
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
80174
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