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Mad2L1 Polyclonal Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

Mad2L1 is required for the execution of the mitotic checkpoint which monitors the process of kinetochore spindle attachment and delays the onset of anaphase when this process is not complete. It inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.

Synonyms

HsMAD 2; MAD 2; MAD 2A; MAD2 like 1; MAD2 like protein 1; MAD2 mitotic arrest deficient like 1; Mitotic arrest deficient yeast homolog like 1; MD2L1_HUMAN.

Gene ID

4085

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Immunogen

131-205/205

Target

Mad2L1

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic peptide derived from human Mad2L1

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4085

Predicted Cross Reactivity

Human, Mouse, Rat, Cow, Pig, Horse, Chicken, Rabbit

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