Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Phospho-Tuberin (Ser1418) Polyclonal Antibody, AbBy Fluor™ 750 Conjugated

Selected Variant

bs-5612R-BF750

Size: 100 µL

Product Specifications

Background

Tuberin, or TSC2 (Tuberous sclerosis complex), is implicated as a tumor suppressor. It may function in vesicular transport, and may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between hamartin (TSC1) and tuberin may facilitate vesicular docking. It specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth. Mutations in tuberin lead to constitutive activation of RAP1A in tumors. At least three isoforms of Tuberin exist.

Synonyms

TSC2phospho S1410; FLJ43106; LAM; TSC2; TSC2_HUMAN; TSC4; Tuberin; Tuberous sclerosis 2 protein.

Gene ID

7249

Modification Site

Ser1418

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Phospho-Tuberin (Ser1418)

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 750

Source

KLH conjugated synthetic phosphopeptide derived from human Tuberin around the phosphorylation site of Ser1418

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

749nm/775nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

7249

Predicted Cross Reactivity

Dog, Cow, Pig, Horse, Chicken

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Anti-TAOK1 Antibody Picoband®
A07063-1-carrier-free 100 µg/Vial

Anti-TAOK1 Antibody Picoband®

Sign In for Pricing
View Details
Ksp-Cadherin / CDH16 (CDH16/1071), 0.2mg/mL
BNUB1071-500 1x 500 µL

Ksp-Cadherin / CDH16 (CDH16/1071), 0.2mg/mL

Sign In for Pricing
View Details
CD44 Standard (156-3C11), 0.2mg/mL
BNUB0460-500 1x 500 µL

CD44 Standard (156-3C11), 0.2mg/mL

Sign In for Pricing
View Details
MTCO1 Rabbit Polyclonal Antibody
HA500517 100 µL

MTCO1 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Smooth Muscle Actin (1A4), CF680R conjugate, 0.1mg/mL
BNC810665-100 1x 100 µL

Smooth Muscle Actin (1A4), CF680R conjugate, 0.1mg/mL

Sign In for Pricing
View Details