Phospho-PRKCQ (Ser695) Polyclonal Antibody, FITC Conjugated

Product Specifications

Background

This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR) -mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.

Synonyms

PRKCQphospho S695; PKCSer695; PKC thetaphospho S695; PKC 0; PRKCQ; PKC0; Prkcq; PRKCT; Protein kinase C theta; Protein kinase C theta type; Protein Kinase Ctheta; KPCT_HUMAN; nPKC theta; nPKC-theta; nPKCtheta.

Gene ID

18761

Modification Site

Ser695

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Target

Phospho-PRKCQ (Ser695)

Clonality

Polyclonal

Isotype

IgG

Conjugation

FITC

Source

KLH conjugated synthetic phosphopeptide derived from mouse PRKCQ around the phosphorylation site of Ser695

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

18761

Predicted Cross Reactivity

Human, Mouse, Rat

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP2-97874APC 0.1 mL

Rabbit Polyclonal CEACAM21 Antibody [Allophycocyanin]

Ask

View Details

20330124-1 1 mg

Goat Anti-Guinea Pig IgG (H&L) Antibody (Polyclonal IgG) - FITC

Ask

View Details

MBS1010357-01 1 mg (E-Coli)

Recombinant Pasteurella multocida Dermonecrotic toxin (toxA), partial

Ask

View Details

MBS1010357-02 1 mg (Yeast)

Recombinant Pasteurella multocida Dermonecrotic toxin (toxA), partial

Ask

View Details

TP301954 20 µg

NBL1 (NM_005380) Human Recombinant Protein

Ask

View Details

MBS1391840-01 0.02 mg (E-Coli)

Recombinant Gorilla gorilla gorilla Agouti-signaling protein (ASIP)

Ask

View Details