Phospho-PRKCQ (Ser676) Polyclonal Antibody, Cy3 Conjugated
Product Specifications
Background
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR) -mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
Synonyms
PRKCQphospho S676; PKCSer676; PKC thetaphospho S676; PKC 0; PRKCQ; PKC0; Prkcq; PRKCT; Protein kinase C theta; Protein kinase C theta type; Protein Kinase Ctheta; KPCT_HUMAN; nPKC theta; nPKC-theta; nPKCtheta.
Gene ID
5588
Modification Site
Ser676
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Target
Phospho-PRKCQ (Ser676)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy3
Source
KLH conjugated synthetic phosphopeptide derived from human PRKCQ around the phosphorylation site of Ser676
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
512,550nm/570,615nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5588
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7173513 Inquire
Rabbit anti-Escherichia coli O7:K1 (strain IAI39/ExPEC) rpsP Polyclonal Antibody
Ask
View Details 