Phospho-PAK1 (Thr212) Polyclonal Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
Synonyms
PAK1Thr212; PAK1phospho T212; Alpha PAK; Alpha-PAK; MGC130000; MGC130001; p21 activated kinase 1; p21 protein Cdc42/Rac activated kinase 1; p21-activated kinase 1; p21/Cdc42/Rac1 activated kinase 1 yeast Ste20 related; p21/Cdc42/Rac1 activated kinase 1; p21/Cdc42/Rac1-activated kinase 1 STE20 homolog, yeast; p65 PAK; p65-PAK; PAK alpha; PAK-1; Pak1; PAK1_HUMAN; Paka; PAKalpha; Protein kinase MUK2; Rac/p21-activated kinase; Serine/threonine-protein kinase PAK 1; STE20 homolog yeast; STE20 homolog yeast.
Gene ID
5058
Modification Site
Thr212
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Phospho-PAK1 (Thr212)
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 647
Source
KLH conjugated synthetic phosphopeptide derived from human PAK1 around the phosphorylation site of Thr212
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/665nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5058
Predicted Cross Reactivity
Dog, Rabbit
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC942216-500 1x 500 µL
CD50 / ICAM3 (CG106), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040146-500 1x 500 µL
CD10 (CB-CALLA), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680495-100 1x 100 µL
SUMO-1 (SM1/495), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC942951-100 1x 100 µL
CDX2 (GI Epithelial Marker) (CDX2/2951R), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC041680-100 1x 100 µL
CD45RA (Leukocyte Marker) (K4B5), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details