STK4 Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
Synonyms
KRS2; MST1; YSK3; STK4
Gene ID
6789
Swiss Prot
Q13043
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
303-487/487
Target
STK4
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
Recombinant fusion protein containing a sequence corresponding to amino acids 303-487 of human STK4 (NP_006273.1) .
Applications
WB, ELISA
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Specificity
KO-Validated
Gene ID URL
6789
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