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CTCF Polyclonal Antibody

Product Specifications

Background

CTCF (CCCTC-binding factor) is a highly conserved zinc finger protein that has been implicated in playing a role in a wide range of regulatory functions, including transcriptional activation/repression, insulation, imprinting, and X chromosome inactivation. A general role for CTCF in the global organisation of chromatin architecture has been proposed. It has been suggested that CTCF is involved, in a heritable manner, in the interplay between DNA methylation, higher-order chromatin structure, and lineage-specific gene expression.

Synonyms

11 zinc finger protein; 11 zinc finger transcriptional repressor; CCCTC binding factor (zinc finger protein) ; CCCTC binding factor; CTCFL paralog; Transcriptional repressor CTCF; CTCF_HUMAN.

Gene ID

10664

Swiss Prot

P49711

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

CTCF

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

Recombinant protein of human CTCF.

Applications

WB, IHC-P

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), IHC-P (1:200-400)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

10664

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