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Beclin 1 Polyclonal Antibody

Product Specifications

Background

This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

Synonyms

ATG6; VPS30; beclin1; Beclin 1; BECN1; beclin-1

Gene ID

8678

Swiss Prot

Q14457

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

181-280/450

Target

Beclin 1

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human Beclin 1 (NP_003757.1) .

Applications

WB, ELISA, IHC-P, IHC-F, IF, Flow-Cyt

Purification

Purified by Protein A.

Concentration

0.5µg/µl

Dilution

WB (WB=1:500-1000), ELISA (ELISA=1:5000-10000), IHC-P (IHC-P=1:400-800), IHC-F (IHC-F=1:400-800), IF (IF=1:100-500), Flow-Cyt (Flow-Cyt=1:100-500)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-55024R

Specificity

KO-Validated

Gene ID URL

8678

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