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Phospho-MEF2D (Ser180) Polyclonal Antibody

Product Specifications

Background

Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT] (4) TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis.

Synonyms

MEF2Dphospho S180; MADS box transcription factor 2 polypeptide D; Mef2d; MEF2D_HUMAN; y myocyte enhancer factor 2D; Myocyte specic enhancer factor 2D; myocyte-specic enhancer factor 2D.

Gene ID

4209

Modification Site

Ser180

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Mouse

Target

Phospho-MEF2D (Ser180)

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic phosphopeptide derived from human MEF2D around the phosphorylation site of Ser180

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

4209

Predicted Cross Reactivity

Human, Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit

Curated Selection

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